Tuesday, July 8, 2025

Woman Loses 320 Pounds and Heals from Rare Skin Disease – Her Incredible Journey

Capture from British media Daily Mail
Capture from British media Daily Mail

A woman who once weighed 483 pounds (219 kg) has gained attention after losing 320 pounds (145 kg). Along with the weight loss, she also cured a rare skin condition called calciphylaxis.

According to the Daily Mail, Lexi Reed, a 34-year-old female from Indiana, USA, was once severely obese, with her weight reaching about 483 pounds (219 kg) due to binge eating and irregular eating habits. She ate out every day, consuming large amounts of sugary drinks and high-calorie foods. In particular, her excessive consumption of fast food, combined with a lack of exercise, caused her weight to increase rapidly.

This led to significant difficulties in her daily life. Simple tasks like breathing, walking short distances, sitting in restaurant chairs, enjoying theme park rides, or buying clothes became challenging for Reed.

Reed decided to lose weight as a friend proposed a 30-day challenge. Cheyenne, Reed’s close friend, encouraged Reed to participate in a challenge to change her lifestyle, prohibiting dining out, drinking alcohol, or consuming sodas while committing to exercise and healthy eating habits. Though Reed thought it would be difficult, she started her diet with her friend’s unwavering support.

Reed began cooking meals at home. Her diet included eggs, broccoli, various vegetables, and fresh foods like chicken. She increased her intake of vegetables and foods rich in protein while consuming almonds, bananas, peanut butter, water, and unsweetened tea as snacks. Reed also started exercising, going to the gym and working out at home as she lost weight. As a result, she lost 320 pounds in two years.

From Diagnosis to Recovery of Calciphylaxis, A Rare Skin Disease

During her weight loss journey, Reed was diagnosed with calciphylaxis, a rare skin disease. This disease causes calcium deposits in blood vessels and blocks blood flow, leading to skin blisters and hardening. Reed’s skin on her stomach and thighs turned black, and wounds appeared. She had to inject medication into her skin for over a year and treat her wounds weekly.

As a result, Reed successfully lost weight and managed to heal from calciphylaxis completely. Ultimately, she lost 320 pounds, bringing her weight to 163 pounds. Reed stated, “We didn’t have a meal plan, surgery, personal trainer, but what we did have was each other and the motivation within to work hard every single day.” She acknowledged that while calciphylaxis is not directly related to weight, she believes her weight loss contributed to alleviating the symptoms of the disease. She also hoped others would take steps toward better health, emphasizing that small changes can lead to significant results.

Calciphylaxis, the disease Reed suffered from, causes lumps or ulcers under the skin, discoloration, and blood clots. While its exact cause remains unknown, it’s often seen in people with chronic kidney disease. The complications can be severe, including excruciating pain, large and deep ulcers, blood infections, and even death. Treatment typically focuses on symptom relief, including dialysis or surgical removal of affected skin tissue if kidney function is impaired.

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